Zhonghua yi shi za zhi

[This article belongs to Volume - 53, Issue - 08]

Abstract : Obesity characterized by body fat excess is associated with pathologies such as cardiovascular disease, diabetes and metabolic syndrome. This study aims to estimate the prevalence of metabolic disorders associated with obesity and determine their association with anthropometric parameters and adiposity in a sample from the Khouribga province in Morocco. A cross-sectional study was conducted on 265 women of 18yrs and over, from urban and rural area in Khouribga province. Height, weight, hip circumference, waist circumference and blood pressure were measured and BMI and WHR were calculated. Non-anthropometric indices were also calculated: lipid accumulation product (LAP), Body adiposity index (BAI), Weight to Height Ratio (WhtR). The prevalence of General (BMI>30) and abdominal obesity (WC>88) were 44% and 78% respectively and that of Hypertension was 33%. The metabolic disorders were also prevalent in the study sample : hypercholesterolemia (HTChol) (4.6%), hyperglycemia (Hgly) (24.1%), hypertriglyceridemia (HTG) (28.2%) and hyperuricemia (HUc) (31.7%). Hgly, HTG and HU prevalences increase with age and BMI. Predictive analysis by binary logistic regression showed that HUc and HTG are associated with both anthropometric measurements and non-anthropometric indices, only LAP gave high ORs. The three parameters BMI, LAP and WhtR have the same importance in predicting hypertension. When these disorders are grouped in the same class as a syndrom, LAP is the best discriminating predictor by the AUC of its ROC curve and the very highly significant Odd Ratio. This study provides data on the prevalence of metabolic disorders associated with cardiovascular problems in the study province. It also revealed the LAP as a precise tool to predicting risk factors for cardiovascular diseases in undiagnosed people whith high risk of developing these pathologies.