The objective of this study was to evaluate the implementation of Community Health Volunteers (CHV) activities in the province of Beni Mellal in Morocco, and to explore and identify the factors influencing this implementation. We adopted a mixed triangulation research design. The study took place in the Naour commune, the province of Beni Mellal in Morocco, involving 18 CHVs, five healthcare professionals, and the CHV program coordinator. Face-to-face questionnaires and semi-structured interviews were used to collect data. Factors that could influence the intervention of CHVs were the selection method, affiliation with the commune, relationship between CHVs and healthcare personnel, CHV training, trainer training, training themes, activities supervision and support from healthcare personnel, use of informational materials, and lack of financial motivation. Some barriers perceived by CHVs and professionals included the quality of the telephone network, understanding, acceptance of CHVs roles, responsibilities by the population, and language barriers. Several factors and perceived barriers could influence the healthcare activities of CHVs. Strengthening supervision, training, and financial motivation could improve the performance of these volunteers.